A complete list of publications can also be found on Google Scholar here. A list of our contributions in conferences and meetings can be found here.
41. Sofia Falia Saravanou, Thomai Samouilidou, Constantinos Tsitsilianis, Stavros Taraviras, George Pasparakis (2025) Injectable and 3D-Printable Semi-Interpenetrating Polymer Networks Based on Modified Sodium Alginate for Cell Spheroid Formation Biomacromolecules, 26, 1, 567–578
40. Aikaterini Gialouri, Sofia Falia Saravanou, Konstantinos Loukelis, Maria Chatzinikolaidou, George Pasparakis, Nikolaos (2023) Bouropoulos Thermoresponsive Alginate-Graft-pNIPAM/Methyl Cellulose 3D-Printed Scaffolds Promote Osteogenesis In Vitro Gels, 9(12), 984; https://doi.org/10.3390/gels9120984
39. SF Saravanou, C Tsitsilianis, G Pasparakis (2023) Harnessing the Interplay of Triple Cross-Linked Hydrogels toward Multiresponsive Alginate-Based Injectable Gels for 3D Printing Bioapplications ACS Macro Letters 12, 1614-1622, doi.org/10.1021/acsmacrolett.3c00470
38. Sofia Falia Saravanou, Konstantinos Ioannidis, Andreas Dimopoulos, Alexandra Paxinou, Fotoula Kounelaki, Sevilli Maria Varsami, Constantinos Tsitsilianis, Ioannis Papantoniou, George Pasparakis (2023) Dually crosslinked injectable alginate-based graft copolymer thermoresponsive hydrogels as 3D printing bioinks for cell spheroid growth and release Carbohydrate Polymers, 120790 doi.org/10.1016/j.carbpol.2023.120790
37. SE Bakhtiari, F Joubert, G Pasparakis, S Brocchini, GR Williams (2023) Nanoparticle forming polyelectrolyte complexes derived from well-defined block copolymers European Polymer Journal 189, 111977 doi.org/10.1016/j.eurpolymj.2023.111977
36. Christopher Barnett, Fanny Joubert, Alexandra Iliopoulou, Raúl Sánchez Álvarez, George Pasparakis (2023) Photochemical Internalization Using Natural Anticancer Drugs, Antimetabolites, and Nanoformulations: A Systematic Study against Breast and Pancreatic Cancer Cell Lines Molecular Pharmaceutics 20, 3, 1818–1841 doi.org/10.1021/acs.molpharmaceut.2c01012
35. George Pasparakis (2022) Recent developments in the use of gold and silver nanoparticles in biomedicine WIREs Nanomedicine and Nanobiotechnology 14 e1817 doi: doi.org/10.1002/wnan.1817
34. Michał Patrzałek, Adam Zieliński, George Pasparakis, Maria Vamvakaki, Anna Ruszczyńska, Ewa Bulska, Anna Kajetanowicz, and Karol Grela (2022) Testing diverse strategies for ruthenium catalyst removal after aqueous homogeneous olefin metathesis Journal of Organometallic Chemistry 965–966, 122320. doi: doi.org/10.1016/j.jorganchem.2022.122320
33. Mina Emamzadeh, and George Pasparakis (2021) Polymer Coated Gold Nanoshells for Combinational Photochemotherapy of Pancreatic Cancer with Gemcitabine Scientific Reports 11, Article number: 9404.
32. George Pasparakis, Constantinos Tsitsilianis (2020) LCST polymers: Thermoresponsive nanostructured assemblies towards bioapplications Polymer 211, 123146 (invited review article).
31. Fanny Joubert, and George Pasparakis (2020) Well-defined backbone degradable polymer-drug conjugates synthesized by Reversible Addition-Fragmentation Chain-Transfer Polymerization Journal of Polymer Science 58 (14), 2010-2021.
30. F Fatimah, Z Aytac, T Uyar, G Pasparakis, GR Williams (2020) An Exploration of Electrospun Fibers Containing Drug-Cyclodextrin Inclusion Complexes Pharmaceutical Sciences & Research 7 (1), 5
29. Fanny Joubert, Peyton Cheong Phey Denn, Yujie Guo, George Pasparakis (2019). Comparison of Thermoresponsive Hydrogels Synthesized by Conventional Free Radical and RAFT Polymerization Materials 12 (17), 2697.
28. Brenda Sanchez-Vazquez, Jong Bong Lee, Margarita Strimaite, Asma Buanz, Russell Bailey, Pavel Gershkovich, George Pasparakis, Gareth R Williams (2019). Solid lipid nanoparticles self-assembled from spray dried microparticles International Journal of Pharmaceutics 572, 118784.
27. Amaral, A. J. R., & Pasparakis, G. (2019). Cell membrane engineering with synthetic materials: applications in cell spheroids, cellular glues and microtissue formation Acta Biomaterialia 90, 21-36.
26. Emamzadeh, M., Emamzadeh, M., & Pasparakis, G. (2019) Dual Controlled Delivery of Gemcitabine and Cisplatin using Polymer-Modified Thermosensitive Liposomes for Pancreatic Cancer ACS Applied Bio Materials 2 (3), pp 1298–1309. DOI: 10.1021/acsabm.9b00007
25. Emamzadeh, M., Desmaële, D., Couvreur, P., & Pasparakis, G. (2018) Dual Controlled Delivery of Squalenoyl-Gemcitabine and Paclitaxel using Thermo-Responsive Polymeric Micelles for Pancreatic Cancer Journal of Materials Chemistry B, 6, 2230-2239 DOI:10.1039/C7TB02899G
24. Joubert, F., & Pasparakis, G. (2018). Hierarchically designed hybrid nanoparticles for combinational photochemotherapy against a pancreatic cancer cell line Journal of Materials Chemistry B, 6, 1095-1104 doi: 10.1039/C7TB03261G
23. Amaral, A. J. R., Emamzadeh M., & Pasparakis, G. (2018). Transiently malleable multi-healable hydrogel nanocomposites based on responsive boronic acid copolymers Polymer Chemistry, 9, 525-537. doi: 10.1039/C7PY01202K
22. Quirós, J., Amaral, A. J. R., Pasparakis, G., Williams, G.R., & Rosal, R. (2017). Electrospun boronic acid-containing polymer membranes as fluorescent sensors for bacteria detection. Reactive and Functional Polymers, 121, 23-31. https://doi.org/10.1016/j.reactfunctpolym.2017.10.007
21. Amaral, A. J. R., & Pasparakis, G. (2017). Stimuli responsive self-healing polymers: gels, elastomers and membranes. Polymer Chemistry, 8, 6464-6484 doi: 10.1039/C7PY01386H
20. Joubert, F., Martin, L., Perrier, S., & Pasparakis, G. (2017). Development of a gemcitabine-polymer conjugate with prolonged cytotoxicity against a pancreatic cancer cell line. ACS Macro Letters , 6, 535–540. doi: 10.1021/acsmacrolett.7b00160
19. Sanchez-Vazquez, B., Amaral, A. J., Yu, D. G., Pasparakis, G., & Williams, G. R. (2016). Electrosprayed Janus Particles for Combined Photo-Chemotherapy. AAPS PharmSciTech. doi:10.1208/s12249-016-0638-4
18. Amaral, A. J. R., & Pasparakis, G. (2016). Rapid Formation of Cell Aggregates and Spheroids Induced by a “Smart” Boronic Acid Copolymer. ACS Applied Materials & Interfaces, 8 (35), 22930–22941. doi: 10.1021/acsami.6b07911
17. Amaral, A. J. R., & Pasparakis, G. (2015). Macromolecular cell surface engineering for accelerated and reversible cellular aggregation. Chemical Communications, 51 (99), 17556-17559. doi:10.1039/c5cc07001e
16. Pasparakis, G., Manouras, T., Vamvakaki, M., & Argitis, P. (2014). Harnessing photochemical internalization with dual degradable nanoparticles for combinatorial photo-chemotherapy. Nature Communications, 5, 3623. doi:10.1038/ncomms4623
15. Pasparakis, G. (2013). Light-induced generation of singlet oxygen by naked gold nanoparticles and its implications to cancer cell phototherapy. Small, 9 (24), 4130-4134. doi:10.1002/smll.201301365
14. Siddique, H., Peeva, L. G., Livingston, A. G., Stoikos, K., Pasparakis, G., & Vamvakaki, M. (2013). Membranes for organic solvent nanofiltration based on preassembled nanoparticles. Industrial and Engineering Chemistry Research, 52 (3), 1109-1121. doi:10.1021/ie202999b
13. Pasparakis, G., Manouras, T., Argitis, P., & Vamvakaki, M. (2012). Photodegradable polymers for biotechnological applications. Macromolecular Rapid Communications, 33 (3), 183-198. doi:10.1002/marc.201100637
12. Pasparakis, G., Manouras, T., Selimis, A., Vamvakaki, M., & Argitis, P. (2011). Laser-induced cell detachment and patterning with photodegradable polymer substrates. Angewandte Chemie International Edition, 50 (18), 4142-4145. doi:10.1002/anie.201007310
11. Pasparakis, G., & Vamvakaki, M. (2011). Multiresponsive polymers: Nano-sized assemblies, stimuli-sensitive gels and smart surfaces. Polymer Chemistry, 2 (6), 1234-1248. doi:10.1039/c0py00424c [top 10 most read papers of March 2011]
10. Xue, X., Pasparakis, G., Halliday, N., Winzer, K., Howdle, S. M., Cramphorn, C. J., Alexander, C. (2011). Synthetic polymers for simultaneous bacterial sequestration and quorum sense interference. Angewandte Chemie International Edition, 50 (42), 9852-9856. doi:10.1002/anie.201103130
9. Pasparakis, G., Krasnogor, N., Cronin, L., Davis, B. G., & Alexander, C. (2010). Controlled polymer synthesis--from biomimicry towards synthetic biology. Chemical Society Reviews, 39 (1), 286-300. doi:10.1039/b809333b
8. Salmaso, S., Caliceti, P., Amendola, V., Meneghetti, M., Magnusson, J. P., Pasparakis, G., & Alexander, C. (2009). Cell up-take control of gold nanoparticles functionalized with a thermoresponsive polymer. Journal of Materials Chemistry, 19 (11), 1608-1615. doi:10.1039/b816603j
7. Pasparakis, G., Vamvakaki, M., Krasnogor, N., & Alexander, C. (2009). Diol-boronic acid complexes integrated by responsive polymers - A route to chemical sensing and logic operations. Soft Matter, 5 (20), 3839-3841. doi:10.1039/b911341j
6. Magnússen, J. P., Pasparakis, G., Wang, W., & Alexander, C. (2008). Facile synthesis of biocompatible responsive copolymers inaqueous solutions. American Chemical Society, Polymer Preprints, Division of Polymer Chemistry, 49 (1), 1014-1015.
5. Magnusson, J. P., Khan, A., Pasparakis, G., Saeed, A. O., Wang, W., & Alexander, C. (2008). Ion-sensitive "isothermal" responsive polymers prepared in water. Journal of the American Chemical Society, 130 (33), 10852-10853. doi:10.1021/ja802609r
4. Pasparakis, G., & Alexander, C. (2008). Sweet talking double hydrophilic block copolymer vesicles. Angewandte Chemie International Edition, 47 (26), 4847-4850. doi:10.1002/anie.200801098 [accepted as Very Important Paper – appeared in Nature Materials 7, 523-525 (2008), News & Views section]
3. Pasparakis, G., Cockayne, A., & Alexander, C. (2007). Control of bacterial aggregation by thermoresponsive glycopolymers. Journal of the American Chemical Society, 129 (36), 11014-11015. doi:10.1021/ja074349z
2. Pasparakis, G., & Alexander, C. (2007). Synthetic polymers for capture and detection of microorganisms. Analyst, 132 (11), 1075-1082. doi:10.1039/b705097f [top 10 most accessed articles – November-December 2007]
1. Pasparakis, G., & Bouropoulos, N. (2006). Swelling studies and in vitro release of verapamil from calcium alginate and calcium alginate-chitosan beads. International Journal of Pharmaceutics, 323 (1-2), 34-42. doi:10.1016/j.ijpharm.2006.05.054
10.1039/C7PY01202K [Top 25 Hottest Articles, July-September 2006 No 13, October-December 2006 No 18]
41. Sofia Falia Saravanou, Thomai Samouilidou, Constantinos Tsitsilianis, Stavros Taraviras, George Pasparakis (2025) Injectable and 3D-Printable Semi-Interpenetrating Polymer Networks Based on Modified Sodium Alginate for Cell Spheroid Formation Biomacromolecules, 26, 1, 567–578
40. Aikaterini Gialouri, Sofia Falia Saravanou, Konstantinos Loukelis, Maria Chatzinikolaidou, George Pasparakis, Nikolaos (2023) Bouropoulos Thermoresponsive Alginate-Graft-pNIPAM/Methyl Cellulose 3D-Printed Scaffolds Promote Osteogenesis In Vitro Gels, 9(12), 984; https://doi.org/10.3390/gels9120984
39. SF Saravanou, C Tsitsilianis, G Pasparakis (2023) Harnessing the Interplay of Triple Cross-Linked Hydrogels toward Multiresponsive Alginate-Based Injectable Gels for 3D Printing Bioapplications ACS Macro Letters 12, 1614-1622, doi.org/10.1021/acsmacrolett.3c00470
38. Sofia Falia Saravanou, Konstantinos Ioannidis, Andreas Dimopoulos, Alexandra Paxinou, Fotoula Kounelaki, Sevilli Maria Varsami, Constantinos Tsitsilianis, Ioannis Papantoniou, George Pasparakis (2023) Dually crosslinked injectable alginate-based graft copolymer thermoresponsive hydrogels as 3D printing bioinks for cell spheroid growth and release Carbohydrate Polymers, 120790 doi.org/10.1016/j.carbpol.2023.120790
37. SE Bakhtiari, F Joubert, G Pasparakis, S Brocchini, GR Williams (2023) Nanoparticle forming polyelectrolyte complexes derived from well-defined block copolymers European Polymer Journal 189, 111977 doi.org/10.1016/j.eurpolymj.2023.111977
36. Christopher Barnett, Fanny Joubert, Alexandra Iliopoulou, Raúl Sánchez Álvarez, George Pasparakis (2023) Photochemical Internalization Using Natural Anticancer Drugs, Antimetabolites, and Nanoformulations: A Systematic Study against Breast and Pancreatic Cancer Cell Lines Molecular Pharmaceutics 20, 3, 1818–1841 doi.org/10.1021/acs.molpharmaceut.2c01012
35. George Pasparakis (2022) Recent developments in the use of gold and silver nanoparticles in biomedicine WIREs Nanomedicine and Nanobiotechnology 14 e1817 doi: doi.org/10.1002/wnan.1817
34. Michał Patrzałek, Adam Zieliński, George Pasparakis, Maria Vamvakaki, Anna Ruszczyńska, Ewa Bulska, Anna Kajetanowicz, and Karol Grela (2022) Testing diverse strategies for ruthenium catalyst removal after aqueous homogeneous olefin metathesis Journal of Organometallic Chemistry 965–966, 122320. doi: doi.org/10.1016/j.jorganchem.2022.122320
33. Mina Emamzadeh, and George Pasparakis (2021) Polymer Coated Gold Nanoshells for Combinational Photochemotherapy of Pancreatic Cancer with Gemcitabine Scientific Reports 11, Article number: 9404.
32. George Pasparakis, Constantinos Tsitsilianis (2020) LCST polymers: Thermoresponsive nanostructured assemblies towards bioapplications Polymer 211, 123146 (invited review article).
31. Fanny Joubert, and George Pasparakis (2020) Well-defined backbone degradable polymer-drug conjugates synthesized by Reversible Addition-Fragmentation Chain-Transfer Polymerization Journal of Polymer Science 58 (14), 2010-2021.
30. F Fatimah, Z Aytac, T Uyar, G Pasparakis, GR Williams (2020) An Exploration of Electrospun Fibers Containing Drug-Cyclodextrin Inclusion Complexes Pharmaceutical Sciences & Research 7 (1), 5
29. Fanny Joubert, Peyton Cheong Phey Denn, Yujie Guo, George Pasparakis (2019). Comparison of Thermoresponsive Hydrogels Synthesized by Conventional Free Radical and RAFT Polymerization Materials 12 (17), 2697.
28. Brenda Sanchez-Vazquez, Jong Bong Lee, Margarita Strimaite, Asma Buanz, Russell Bailey, Pavel Gershkovich, George Pasparakis, Gareth R Williams (2019). Solid lipid nanoparticles self-assembled from spray dried microparticles International Journal of Pharmaceutics 572, 118784.
27. Amaral, A. J. R., & Pasparakis, G. (2019). Cell membrane engineering with synthetic materials: applications in cell spheroids, cellular glues and microtissue formation Acta Biomaterialia 90, 21-36.
26. Emamzadeh, M., Emamzadeh, M., & Pasparakis, G. (2019) Dual Controlled Delivery of Gemcitabine and Cisplatin using Polymer-Modified Thermosensitive Liposomes for Pancreatic Cancer ACS Applied Bio Materials 2 (3), pp 1298–1309. DOI: 10.1021/acsabm.9b00007
25. Emamzadeh, M., Desmaële, D., Couvreur, P., & Pasparakis, G. (2018) Dual Controlled Delivery of Squalenoyl-Gemcitabine and Paclitaxel using Thermo-Responsive Polymeric Micelles for Pancreatic Cancer Journal of Materials Chemistry B, 6, 2230-2239 DOI:10.1039/C7TB02899G
24. Joubert, F., & Pasparakis, G. (2018). Hierarchically designed hybrid nanoparticles for combinational photochemotherapy against a pancreatic cancer cell line Journal of Materials Chemistry B, 6, 1095-1104 doi: 10.1039/C7TB03261G
23. Amaral, A. J. R., Emamzadeh M., & Pasparakis, G. (2018). Transiently malleable multi-healable hydrogel nanocomposites based on responsive boronic acid copolymers Polymer Chemistry, 9, 525-537. doi: 10.1039/C7PY01202K
22. Quirós, J., Amaral, A. J. R., Pasparakis, G., Williams, G.R., & Rosal, R. (2017). Electrospun boronic acid-containing polymer membranes as fluorescent sensors for bacteria detection. Reactive and Functional Polymers, 121, 23-31. https://doi.org/10.1016/j.reactfunctpolym.2017.10.007
21. Amaral, A. J. R., & Pasparakis, G. (2017). Stimuli responsive self-healing polymers: gels, elastomers and membranes. Polymer Chemistry, 8, 6464-6484 doi: 10.1039/C7PY01386H
20. Joubert, F., Martin, L., Perrier, S., & Pasparakis, G. (2017). Development of a gemcitabine-polymer conjugate with prolonged cytotoxicity against a pancreatic cancer cell line. ACS Macro Letters , 6, 535–540. doi: 10.1021/acsmacrolett.7b00160
19. Sanchez-Vazquez, B., Amaral, A. J., Yu, D. G., Pasparakis, G., & Williams, G. R. (2016). Electrosprayed Janus Particles for Combined Photo-Chemotherapy. AAPS PharmSciTech. doi:10.1208/s12249-016-0638-4
18. Amaral, A. J. R., & Pasparakis, G. (2016). Rapid Formation of Cell Aggregates and Spheroids Induced by a “Smart” Boronic Acid Copolymer. ACS Applied Materials & Interfaces, 8 (35), 22930–22941. doi: 10.1021/acsami.6b07911
17. Amaral, A. J. R., & Pasparakis, G. (2015). Macromolecular cell surface engineering for accelerated and reversible cellular aggregation. Chemical Communications, 51 (99), 17556-17559. doi:10.1039/c5cc07001e
16. Pasparakis, G., Manouras, T., Vamvakaki, M., & Argitis, P. (2014). Harnessing photochemical internalization with dual degradable nanoparticles for combinatorial photo-chemotherapy. Nature Communications, 5, 3623. doi:10.1038/ncomms4623
15. Pasparakis, G. (2013). Light-induced generation of singlet oxygen by naked gold nanoparticles and its implications to cancer cell phototherapy. Small, 9 (24), 4130-4134. doi:10.1002/smll.201301365
14. Siddique, H., Peeva, L. G., Livingston, A. G., Stoikos, K., Pasparakis, G., & Vamvakaki, M. (2013). Membranes for organic solvent nanofiltration based on preassembled nanoparticles. Industrial and Engineering Chemistry Research, 52 (3), 1109-1121. doi:10.1021/ie202999b
13. Pasparakis, G., Manouras, T., Argitis, P., & Vamvakaki, M. (2012). Photodegradable polymers for biotechnological applications. Macromolecular Rapid Communications, 33 (3), 183-198. doi:10.1002/marc.201100637
12. Pasparakis, G., Manouras, T., Selimis, A., Vamvakaki, M., & Argitis, P. (2011). Laser-induced cell detachment and patterning with photodegradable polymer substrates. Angewandte Chemie International Edition, 50 (18), 4142-4145. doi:10.1002/anie.201007310
11. Pasparakis, G., & Vamvakaki, M. (2011). Multiresponsive polymers: Nano-sized assemblies, stimuli-sensitive gels and smart surfaces. Polymer Chemistry, 2 (6), 1234-1248. doi:10.1039/c0py00424c [top 10 most read papers of March 2011]
10. Xue, X., Pasparakis, G., Halliday, N., Winzer, K., Howdle, S. M., Cramphorn, C. J., Alexander, C. (2011). Synthetic polymers for simultaneous bacterial sequestration and quorum sense interference. Angewandte Chemie International Edition, 50 (42), 9852-9856. doi:10.1002/anie.201103130
9. Pasparakis, G., Krasnogor, N., Cronin, L., Davis, B. G., & Alexander, C. (2010). Controlled polymer synthesis--from biomimicry towards synthetic biology. Chemical Society Reviews, 39 (1), 286-300. doi:10.1039/b809333b
8. Salmaso, S., Caliceti, P., Amendola, V., Meneghetti, M., Magnusson, J. P., Pasparakis, G., & Alexander, C. (2009). Cell up-take control of gold nanoparticles functionalized with a thermoresponsive polymer. Journal of Materials Chemistry, 19 (11), 1608-1615. doi:10.1039/b816603j
7. Pasparakis, G., Vamvakaki, M., Krasnogor, N., & Alexander, C. (2009). Diol-boronic acid complexes integrated by responsive polymers - A route to chemical sensing and logic operations. Soft Matter, 5 (20), 3839-3841. doi:10.1039/b911341j
6. Magnússen, J. P., Pasparakis, G., Wang, W., & Alexander, C. (2008). Facile synthesis of biocompatible responsive copolymers inaqueous solutions. American Chemical Society, Polymer Preprints, Division of Polymer Chemistry, 49 (1), 1014-1015.
5. Magnusson, J. P., Khan, A., Pasparakis, G., Saeed, A. O., Wang, W., & Alexander, C. (2008). Ion-sensitive "isothermal" responsive polymers prepared in water. Journal of the American Chemical Society, 130 (33), 10852-10853. doi:10.1021/ja802609r
4. Pasparakis, G., & Alexander, C. (2008). Sweet talking double hydrophilic block copolymer vesicles. Angewandte Chemie International Edition, 47 (26), 4847-4850. doi:10.1002/anie.200801098 [accepted as Very Important Paper – appeared in Nature Materials 7, 523-525 (2008), News & Views section]
3. Pasparakis, G., Cockayne, A., & Alexander, C. (2007). Control of bacterial aggregation by thermoresponsive glycopolymers. Journal of the American Chemical Society, 129 (36), 11014-11015. doi:10.1021/ja074349z
2. Pasparakis, G., & Alexander, C. (2007). Synthetic polymers for capture and detection of microorganisms. Analyst, 132 (11), 1075-1082. doi:10.1039/b705097f [top 10 most accessed articles – November-December 2007]
1. Pasparakis, G., & Bouropoulos, N. (2006). Swelling studies and in vitro release of verapamil from calcium alginate and calcium alginate-chitosan beads. International Journal of Pharmaceutics, 323 (1-2), 34-42. doi:10.1016/j.ijpharm.2006.05.054
10.1039/C7PY01202K [Top 25 Hottest Articles, July-September 2006 No 13, October-December 2006 No 18]
